課程資訊
課程名稱
書報討論(一)
SEMINAR (B.S.)(1) 
開課學期
97-1 
授課對象
生命科學系  
授課教師
鄭貽生 
課號
LS4001 
課程識別碼
B01 40010 
班次
04 
學分
全/半年
半年 
必/選修
必帶 
上課時間
星期二7,8(14:20~16:20) 
上課地點
生科4B 
備註
與李士傑、謝旭亮合開
限學士班四年級以上 且 限學號末二位被4整除
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/971seminar01 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

本課程以學生輪流上台發表學術演講為主軸,其他同學則需聽講並參予討論。每人每學期以演講一次為原則,並需擔任一次主持人,負責介紹當次演講者背景、演講主題、主持討論和掌控時間等工作。 

課程目標
培養學生檢索、選擇、閱讀期刊論文與演講發表之能力, 同時參予其他同學之演講,藉以獲得學術研究之啟蒙。 
課程要求
97學年度第一學期大四書報討論注意事項
1. 每位同學必須依其興趣邀請一位生命科學相關領域老師(不限本系專任),對其報告論文之選擇、報告內容之組織、及報告技巧予以協助和指導。學生報告時請邀請指導老師出席。
2. 論文之選擇應以2006年至今所發表之生命科學相關領域之SCI期刊的原創性研究文章(original research paper)(不得選擇 review 綜合論述或 notes, short communication, letter to editor 之類短篇文章),並須獲指導老師同意。論文題目應於9月23日12:10pm以前登記,題目相同時以先登記者優先採用。
3. 論文影本應於一週前送交書報討論主持老師每人一份。報告題目及中文摘要,應於前一週星期二12:10pm以email寄送鄭貽生老師,經修改及確認後上傳至Ceiba討論區,並於報告前分發同學。摘要內容應包括:報告人姓名、報告時間、地點、指導老師、論文題目、期刊名(卷期、頁數),中文摘要,以及相關參考文獻。
4. 各類型參考文獻之編寫格式範例如下:
Published papers(cell format)依First Author字母排序
Ayabe, T., Satchell, D.P., Wilson, C.L., Parks, W.C., Selsted, M.E., and Ouellette, A.J. (2000). Secretion of microbicidal α-defensins by intestinal Paneth cells in response to bacteria. Nat. Immunol. 1, 113-118.
Birney, E., Stamatoyannopoulos, J.A., Dutta, A., Guigo, R., Gingeras, T.R., Margulies, E.H., Weng, Z., Snyder, M., Dermitzakis, E.T., Thurman, R.E. et al. (2007). Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447, 799-816.

Electronic journal articles
Loker, WM. (1996 ) "Campesinos" and the crisis of modernization in Latin America. J. Pol. Ecol. 3 (1). Available: http://www.library.arizona.edu/ej/jpe/volume_3/ascii-lokeriso.txt via the Internet. Accessed 1996 Aug 11.
Books
Bates, B. (1992) Bargaining for life: A social history of tuberculosis. Philadelphia: University of Pennsylvania Press. 435 p.
Book chapters
Hansen, B. (1991) New York City epidemics and history for the public. In: AIDS and the historian. Harden, VA, Risse, GB. editors. Bethesda: National Institute of Health. pp. 21-28.

5. 每人報告時間25 ~ 30分鐘,發問及討論15 ~ 20分鐘。由上一個星期報告的同學主持與計時。每位學生於課堂結束交回討論評比表。
6. 報告時請利用 PowerPoint 檔案輔助演講,均應以英文呈現(生物學名宜加註中文名稱) ,字體和圖表均以清晰簡明為原則(如一張投影片只放一個圖或表為宜)。
7. 學期成績,以專題論文報告之準備、現場之表現為主,出席、填寫討論評比表、發問、及隨堂討論亦將列入考量。
8. 表現不佳(成績低於70分)者必須於期末重講。
9. 無故缺席者,一次扣總分5分,遲到一次扣總分一分;遲到20分鐘以上者,以無故缺席論。
 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
 
參考書目
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
演講 
80% 
 
2. 
討論 
10% 
 
3. 
出席 
10% 
 
 
課程進度
週次
日期
單元主題
第1週
09/16  李士傑老師講解規則 
第2週
09/23  準備週 
第3週
09/30  1.劉家宏 A Race for Survival: Can Bromus tectorum Seeds Escape Pyrenophora semeniperda-caused Mortality by Germinating Quickly? Annals of Botany, 99:907-914, 2007<br><br>2.林育生Protein ubiquitination is modulated by O-GlcNAc glycosylation FASEB J. 22:2901–2911, 2008 
第4週
10/07  3.吳庭光 Molecular phylogeny of Chaetodon (Teleostei: Chaetodontidae) in the Indo-West Pacific: evolution in geminate species pairs and species groups. Raffl. Bull. Zool. Suppl., 14:77-86, 2007<br><br>4.謝舒丞 Danggui Buxue Tang–A Chinese herbal decoction activates the phosphorylations of extracellular signal-regulated kinase and estrogen receptor a in cultured MCF-7 cells. FEBS LETTERS, 581:233-240, 2007  
第5週
10/14  5.李崢嶸 Genomic Analysis Reveals Age-Dependent Innate Immune Responses to SARS Coronavirus Tracey Baas. Journal of Virology,2008 <br><br>6.李岱威 Phorbol 12-myristate 13-acetate-activated protein kinase C increased migratory activity of subconjunctival fibroblasts via stress-activated protein kinase pathways in Molecular Vision. 13:2320-2327, 2007 
第6週
10/21  7.薛孝亭 Eukaryotic Translation Initiation Factor 5A Is Involved in Pathogen-Induced Cell Death and Development of Disease Symptoms in Arabidopsis Plant Physiology, 148:479-489, 2008<br><br>8.葉潛之Calcium control of endocytic capacity at a CNS synapse.The Journal of Neuroscience, 28:6742-6749, 2008 
第7週
10/28  9.薛穎超 Treatment of chronic autoimmune urticaria with Omalizumab. J. Allergy Clin. Immunol. 121, S226-S227, 2008. <br><br>10.陳依瑩 Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration in Developmental Dynamics 235:606-616, 2006 
第8週
11/04  11.何建鴻 Gamma-aminobutyric acid (GABA) receptor mediates suanzaorentang,a traditional Chinese herb remedy, -induced sleep alteration. Journal of Biomedical Science, 14:285-297, 2007 <br><br>12.盂曾賢 Surface plasmon resonance biosensor detects the downstream events of active PKC in antigen-stimulated mast cells.Biosensors and Bioelectronics 23 (2008) 1652–1658 
第9週
11/11  期中考週 
第10週
11/18  13.蔡宇臣 Phosphatidylinositol-3 Phosphatase Myotubularin-Related Protein 6 Negatively Regulates CD4 T Cells?<br><br>14.李飛葦 Class 1 KNOX genes are not involved in shoot development in the moss Physcomitrella patens <br><br>蔡向榮 In vivo reprogramming of adult pancreatic exocrine cells to b-cells 
第11週
11/25  15.盧映儒 Contact-inhibited chemotaxis in de novo and sprouting blood-vessel growth. PLoS Comput Biol. 2008 Sep 19;4(9):e1000163.[Epub ahead of print]<br><br>16.邱顯壹 Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20:2214-22. 2006 
第12週
12/02  17.謝瑩蓉 Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development. Cell 128:931-946, 2007 <br><br>18.黃啟軒Low X/Y divergence in four pairs of papaya sex-linked genes. Plant J. 53:124-132, 2008 
第13週
12/09  19.徐健翔 Oscillations and variability in the p53 system. Molecular Systems Biology
13 June 2006 <br><br> 20.楊尚樺 Comparison of heavy metal toxicity in life stages (spermiotoxicity, egg toxicity, embryotoxicity and larval toxicity) of Hydroides elegans. Chemosphere, 71:515-528, 2008  
第14週
12/16  21.吳亮均 An increase in intracellular Ca2 is required for the activation of mitochondrial calpain to release AIF during cell death, Cell Death Differ. 2008 Sep 19. [Epub ahead of print]<br><br>22.陳鏡文 B Cell Depletion Therapy in Systemic Lupus Erythematosus Effect on Autoantibody and Antimicrobial Antibody Profiles ARTHRITIS  
第15週
12/23  23.陳瀅淳 Conspicuousness, not eye mimicry, makes "eyespots" effective antipredator signals. Behav. Ecol. Stevens et al. 19: 525-531.<br><br>
24. 張珮瑩 Phototoxicity of phenylenediamine hair dye chemicals in Salmonella typhimurium TA 102 and human skin keratinocyte. Food and Chemical Toxicology 46 (2008)3780-3784
 
第16週
12/30  25.張景賀 Expression Profile of a Degenerating Neo-Y Chromosome in DrosophilaCurrent Biology 16, 1694-1699, 2006<br><br>26.楊軒 A Model for Protein Translation: Polysome Self-Organization Leads to Maximum Protein Synthesis Rates, Biophysical Journal, 92:717–730, 2007 
第17週
01/06  本學期書報討論之回顧、檢討與改進。 
第18週
01/13  期末考週